Recognition of Potentially Novel Human Disease-Associated Pathogens by Implementation of Systematic 16S rRNA Gene Sequencing in the Diagnostic Laboratory

P. Keller, SK Rampini, AC Büchler, G. Eich, RM Wanner, RF Speck, EC Böttger, and GV Bloemberg. Journal of Clinical Microbiology, Sept 2010, p. 3397-3402. Accepted 2 July 2010. This email address is being protected from spambots. You need JavaScript enabled to view it.

Citation: “... Homology analyses were performed using the SmartGene Integrated Database Network System (IDNS) … and NCBI GenBank databases.... During our study, the number of 16S rRNA sequences deposited in the NCBI nucleotide database increased by a factor of 15. The SmartGene IDNS 16S rRNA database, which is a curated database derived from the NCBI repository, increased in size by a factor of 4....”